853015-01-7

Basic information

• Product Name: (E)-2-benzylamino-2-[2-(4-octylphenyl)ethenyl]propane-1,3-diol
• Synonyms: (E)-2-benzylamino-2-[2-(4-octylphenyl)ethenyl]propane-1,3-diol
• CAS NO: 853015-01-7
• Molecular Weight: 395.585
• Mol File: 853015-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-benzylamino-2-[2-(4-octylphenyl)ethenyl]propane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-benzylamino-2-[2-(4-octylphenyl)ethenyl]propane-1,3-diol(853015-01-7)
• EPA Substance Registry System: (E)-2-benzylamino-2-[2-(4-octylphenyl)ethenyl]propane-1,3-diol(853015-01-7)

Safety Data

• Hazardous Substances Data: 853015-01-7(Hazardous Substances Data)

Upstream product

• 49763-66-8 4-octylbenzaldehyde 
• 166964-89-2 4-n-Octyl-β,β'-dibromostyrene 
• 79887-13-1 1-ethynyl-4-octylbenzene 
• 853015-02-8 (E)-2-(4-octylphenyl)-vinylboronic acid 
• 96-26-4 dihydroxyacetone 
• 100-46-9 benzylamine 

Relevant articles and documents

A convenient synthesis of immunosuppressive agent FTY720 using the petasis reaction

A convenient synthesis of immunosuppressive agent FTY720 (1) using the Petasis reaction was developed. 4-Octylbenzaldehyde (9) was converted into 1-ethenyl-4-octylbenzene (11) by two-step synthesis. Hydroboration of 11 using catecholborane and hydrolysis gave (E)-2-(4-octylphenyl)vinylboronic acid (4). The Petasis reaction of 4, dihydroxyacetone (3), and benzylamine following catalytic hydrogenation afforded FTY720 (1).