85302-17-6 Usage
Description
1,6,6-Trimethyl-1,5,6,7-tetrahydro-indazol-4-one is a bicyclic heterocyclic compound with the molecular formula C11H17N2O, belonging to the indazole class. It is a white to off-white crystalline solid that is soluble in organic solvents.
Uses
Used in Pharmaceutical Industry:
1,6,6-Trimethyl-1,5,6,7-tetrahydro-indazol-4-one is used as a GABA-A receptor positive allosteric modulator for its potential role in the treatment of anxiety and other neurological disorders.
Used in Medicinal Chemistry:
1,6,6-Trimethyl-1,5,6,7-tetrahydro-indazol-4-one is used as a precursor in the synthesis of novel indazole-based compounds with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 85302-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,3,0 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 85302-17:
(7*8)+(6*5)+(5*3)+(4*0)+(3*2)+(2*1)+(1*7)=116
116 % 10 = 6
So 85302-17-6 is a valid CAS Registry Number.
85302-17-6Relevant articles and documents
Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles. I. Synthesis of 1,5-Disubstituted 4-Acylpyrazoles
Schenone, Pietro,Mosti, Luisa,Menozzi, Giulia
, p. 1355 - 1361 (2007/10/02)
Reaction of open-chain and cyclic sym-1,3-diones with N,N-dimethylformamide dimethyl acetal gave, generally in high yield, a series of sym-2-dimethylaminomethylene-1,3-diones which reacted with phenylhydrazine and methylhydrazine to afford, generally in satisfactory yield, a number of 1,5-disubstituted 4-acylpyrazoles.The applications and limits of this new pyrazole synthesis are presented and discussed.
