85302-55-2

Upstream product

• 85302-54-1 1,5-Diphenylamino-1,2,3,4,5-pentadeuteriopentamethinium Chloride 
• 7291-22-7 perdeuteriopyridine 
• 85302-53-0 1-(2,4-Dinitrophenyl)-2,3,4,5,6-pentadeuteriopyridinium Chloride 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 91206-26-7 1-phenyl-2,4,4,6-tetradeuterio-1,4-dihydropyridine 
• 91206-28-9 1',6-diphenyl-2-(1',4-dihydropyrid-4'-ylidene)-3,3',4,5'-tetradeuterio-6-aza-3,5-hexadienal 

Relevant academic research and scientific papers

PREPARATION OF 1-PHENYLDIHYDROPYRIDINES POLYDEUTERATED IN THEIR HETEROCYCLIC RING

The pentadeuterated quarternary salt III reacts with aniline to give the pentadeuterated pentamethine salt IV which, on action of triethylamine, gives a mixture of 1-phenylpyridinium chlorides Va-c.The chlorides Va-c are reduced with dithionite or borohydride to mixtures of 1,4-(VIIa-c) or 1,2-dihydropyridines (VIIIa-c), respectively.A procedure has been found for obtaining the 3,4,5-trideuterated or 2,3,4,5,6-pentadeuterated products.