853020-88-9

Basic information

• Product Name: 1'-benzyl-6-methoxy-2,3,4,9-tetrahydrospiro[β-carboline-1,3'-pyrrolidine]
• CAS NO: 853020-88-9
• Molecular Weight: 347.46
• Mol File: 853020-88-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1'-benzyl-6-methoxy-2,3,4,9-tetrahydrospiro[β-carboline-1,3'-pyrrolidine](CAS DataBase Reference)
• NIST Chemistry Reference: 1'-benzyl-6-methoxy-2,3,4,9-tetrahydrospiro[β-carboline-1,3'-pyrrolidine](853020-88-9)
• EPA Substance Registry System: 1'-benzyl-6-methoxy-2,3,4,9-tetrahydrospiro[β-carboline-1,3'-pyrrolidine](853020-88-9)

Safety Data

• Hazardous Substances Data: 853020-88-9(Hazardous Substances Data)

Upstream product

• 775-16-6 N-benzyl-3-pyrrolidinone 
• 66-83-1 5-methoxytryptamine hydrochloride 

Downstream Products

• 853018-52-7 N'-{2-[6-methoxy-1'-(2-phenoxyethyl)-4,9-dihydrospiro[β-carboline-1,3'-pyrrolidin]-2(3H)-yl]ethyl}-N,N-dimethylurea trifluoroacetate 

Relevant articles and documents

NOVEL BETA-CARBOLINES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHSR) ANTAGONISTS

The present invention relates to compounds of Formula (I): Formula (I) wherein R-R, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.