853066-73-6 Usage
General Description
Tributyl[4-(4-fluorophenyl)-6-isopropyl-2-[(2-n-Methyl-n-Methyl sulfonyl)aMino]pyriMidine-5-yl-Methyl]phosphine broMine is a complex chemical compound. It is a phosphorylating reagent used in organic synthesis for the introduction of the phosphine group into various compounds. Tributyl[4-(4-fluorophenyl)-6-isopropyl-2-[(2-n-Methyl-n-Methyl sulfonyl)aMino]pyriMidine-5-yl-Methyl]phosphine broMine contains a phosphine group, a bromine atom, and a pyrimidine ring with various substituents. It is commonly used in the pharmaceutical industry for the synthesis of new drug candidates and in other areas of organic chemistry for the modification of molecules. Due to its complex structure, it is important to handle this chemical with caution and according to proper safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 853066-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,3,0,6 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 853066-73:
(8*8)+(7*5)+(6*3)+(5*0)+(4*6)+(3*6)+(2*7)+(1*3)=176
176 % 10 = 6
So 853066-73-6 is a valid CAS Registry Number.
853066-73-6Relevant articles and documents
Application of flow photochemical bromination in the synthesis of a 5-bromomethylpyrimidine precursor of rosuvastatin: Improvement of productivity and product purity
Sterk, Damjan,Jukic, Marko,Casar, Zdenko
, p. 145 - 151 (2013/03/14)
In this report we present a flow photochemical bromination of a 5-methyl-substituted pyrimidine precursor of rosuvastatin. The study demonstrated that the reaction productivity can be increased markedly with a flow-mode approach compared to a batch-mode synthesis. Indeed, reaction times can be significantly shortened from a range of hours to a range of minutes. Moreover, in addition to process intensification, the study demonstrated that significantly lower overall levels of side products are obtained when photochemical bromination is conducted in a flow mode.
PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM
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Page/Page column 27, (2010/11/25)
Present invention represents process for the preparation of HMG-CoA reductsase inhibitors, in particular rosuvastatin calcium introducing L-malic acid as the source of chirality for the side chain