853102-08-6

Basic information

• Product Name: 5-bromo-N-cyclohexyl-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-amine
• Synonyms: 5-bromo-N-cyclohexyl-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-amine
• CAS NO: 853102-08-6
• Molecular Weight: 404.737
• Mol File: 853102-08-6.mol

Chemical Properties

• CAS DataBase Reference: 5-bromo-N-cyclohexyl-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-N-cyclohexyl-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-amine(853102-08-6)
• EPA Substance Registry System: 5-bromo-N-cyclohexyl-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-amine(853102-08-6)

Safety Data

• Hazardous Substances Data: 853102-08-6(Hazardous Substances Data)

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 931-53-3 Cyclohexyl isocyanide 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Ammonium chloride catalyzed one-pot synthesis of imidazo[1,2-a]pyridines

Ammonium chloride as a very inexpensive and readily available reagent efficiently catalyzes one-pot, three-component Groebke condensation reactions of aldehydes, isocyanides, and 2-aminopyridines or 2-aminopyrimidines in methanol to afford the corresponding imidazo[1,2-a]pyridines in high yields at room temperature.

Facile synthesis of imidazo[1,2-a]pyridines via a one-pot three-component reaction under solvent-free mechanochemical ball-milling conditions

In this work, 3-aminoimidazo[1,2-a]pyridine derivatives have been synthesized by a one-pot three-component condensation reaction of 2-aminopridines, aldehydes and isocyanides under solvent-free mechanochemical ball-milling conditions in good to excellent yields at room temperature. This efficient protocol has many noticeable advantages such as mild reaction conditions, high yields, high atom economy, short reaction times and simple separation. the Partner Organisations 2014.