85311-39-3

Usage

Chemical Family

Belongs to the benzimidazole family

Structure

Contains two amino groups (-NH2) at positions 4 and 7, and two methyl groups (-CH3) at positions 5 and 6

Potential Applications

Known for its potential pharmaceutical and biological activities

Antiviral Properties

Exhibits antiviral properties

Antifungal Properties

Exhibits antifungal properties

Anticancer Properties

Exhibits anticancer properties

Drug Design and Development

Studied for its use in drug design and development

Synthesis of Therapeutic Agents

Used in the synthesis of new therapeutic agents

Interest to Researchers

Of interest to researchers and scientists in the field of medicinal chemistry and pharmaceutical sciences

Upstream product

• 32046-79-0 4,7-dinitro-5,6-dimethylbenzimidazole 
• 582-60-5 5,6-dimethyl-1H-benzo[d]imida-zole 

Downstream Products

• 61587-95-9 5,6-dimethylbenzimidazole-4,7-dione 

Relevant academic research and scientific papers

Ultrafast and Stable Proton Conduction in Polybenzimidazole Covalent Organic Frameworks via Confinement and Activation

Polybenzimidazoles are engineering plastics with superb thermal stability and this specificity has sparked a wide-ranging research to explore proton-conducting materials. Nevertheless, such materials encounter challenging issues owing to phosphoric acid proton carrier leakage and slow proton transport. We report a strategy for designing porous polybenzimidazole frameworks to address these key fundamental issues. The built-in channels are designed to be one-dimensionally extended, unidirectionally aligned, and fully occupied by neat phosphoric acid, while the benzimidazole walls trigger multipoint, multichain, and multitype interactions to spatially confine a phosphoric acid network in pores and facilitate proton conduction via deprotonation. The materials exhibit ultrafast and stable proton conduction for low proton carrier content and activation energy—a set of features highly desired for proton transport. Our results offer a design strategy for the fabrication of porous polybenzimidazoles for use in energy conversion applications.

HETEROCYCLIC QUINONES WITH POTENTIAL ANTITUMOR ACTIVITY A CONVENIENT SYNTHESIS OF 5,6-DIMETHYL-4,7-BENZIMIDAZOLEDIONES

Simple syntheses of 1-substituted 5,6-dimethyl-4,7-benzimidazolediones (Ia-c) are described.The commercially available 5,6-dimethylbenzimidazole was alkylated and nitrated.The corresponding 4,7-dinitro derivatives were reduced to diamines and subsequently oxidized to quinones.