85314-70-1Relevant academic research and scientific papers
Highly Selective Synthesis of Ortho-Prenylated Phenols and Chromans by using a New Bimetallic CuAl-KIT-5 with a 3D-Cage-type Mesoporous Structure
Varghese, Shaji,Anand, Chokkalingam,Dhawale, Dattatray,Mane, Gurudas P.,Wahab, Mohammad A.,Mano, Ajayan,Raj, George Allen Gnana,Nagarajan, Samuthira,Vinu, Ajayan
, p. 899 - 902 (2013/05/08)
A nice piece of KIT: The first synthesis of a new bimetallic 3D-cage-type mesoporous catalyst CuAl-KIT-5 and its remarkable performance for the highly selective synthesis of ortho-prenylated phenols and chromans is reported.
Catalytic performance of nanoscopic, aluminium trifluoride-based catalysts in the synthesis of (all-rac)-α-tocopherol
Coman,Wuttke,Vimont,Daturi,Kemnitz
experimental part, p. 2517 - 2524 (2009/08/14)
A novel nanoscopic, partly hydroxylated aluminium fluoride was prepared in a sol-gel fluorination synthesis and characterised by IR probe molecules. It was shown that this material has, in contrast to high surface area aluminium fluoride (HSAlF3) which is one of the strongest Lewis acids, a low amount of strong Lewis acid sites combined with weak and medium strength Br?nsted sites. Both materials were tested in the synthesis of (all-rac)-α-tocopherol through the condensation of 2,3,6- trimethylhydroquinone (TMHQ) with isophytol (IP). The activity data indicate the partly hydroxylated aluminium fluoride to be a very efficient and highly selective catalyst for (all-rac)-α-tocopherol (>99.9%, for an IP conversion of 100%) whereas high surface area aluminium fluoride is a poor catalyst for this reaction.
Process for the manufacture of chroman derivatives, especially alpha-tocopherol and alkanoates thereof
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Page/Page column 12, (2008/06/13)
The present invention relates to novel processes for the manufacture of chroman derivatives such as α-tocopherol (TCP) and alkanoates thereof, especially α-tocopheryl acetate (TCPA), whereby at least one step of the processes is carried out in the presence of a Lewis acid or a mixture of a Lewis acid with a Bronsted acid as the catalyst under pressure, preferably at an absolute pressure of at least 1.1 bar. As starting materials for the manufacture of TCP and its alkanoates either a mixture of 2,3,5-trimethylhydroquinone (TMHQ) or 2,3,6-trimethylhydroquinone-1-alkanoate (TMHQA) and a compound selected from the group consisting of phytol (pH), isophytol (IP) and (iso)phytol derivatives or 2-phytyl-3,5,6-trimethyl-hydroquinone (PTMHQ)/3-phytyl-2,5,6-trimethylhydroquinone-1-alkanoate (PTMHQA) and/or an isomer thereof are used. Suitable Lewis acids are indium(III) salts and scandium(III) salts. Suitable acid mixtures are iron/iron(II) chloride/hydrogen chloride and zinc(II) chloride/hydrogen chloride.
PRODUCTION OF 2-ALKENYL-3,5,6-TRIMETHYL-1,4-BENZOQUINONES AND THEIR WATER-SOLUBLE FORMS
Byzova, V. N.,Zakharova, E. I.,Zhukova, E. E.,Sarycheva, I. K.,Evstigneeva, R. P.
, p. 2135 - 2140 (2007/10/02)
A method is described for the synthesis of 3,5,6-trimethyl-1,4-benzoquinones containing isoprenoid substituents with hydrocarbon chain lengths between C5 and C20 at position 2 by the condensation of 2,3,5-trimethylhydroquinone or its
