85319-00-2Relevant academic research and scientific papers
Unsymmetrical 1,1-diborated multisubstituted sp3-carbons formed via a metal-free concerted-asynchronous mechanism
Cuenca, Ana B.,Cid, Jessica,García-López, Diego,Carbó, Jorge J.,Fernández, Elena
supporting information, p. 9659 - 9664 (2015/09/28)
We have experimentally proved the unsymmetrical 1,1-diboration of diazo compounds, formed in situ from aldehydes and cyclic and non-cyclic ketones, in the absence of any transition metal complex. The heterolytic cleavage of the mixed diboron reagent, Bpin-Bdan, and the formation of two geminal C-Bpin and C-Bdan bonds has been rationalised based on DFT calculations to occur via a concerted-asynchronous mechanism. Diastereoselection is attained on substituted cyclohexanones and DFT studies provide understanding on the origin of the selectivity. The alkoxide-assisted selective deborylation of Bpin from multisubstituted sp3-carbon and generation of a Bdan stabilized carbanion, easily conducts a selective protodeboronation sequence.
A New Method for Cyclopentanone Annelation
Snider, Barry B.,Cartaya-Marin, Claudia P.
, p. 153 - 157 (2007/10/02)
MeAlCl2-initiated cyclization of enone 6d provides an 85percent yield of a 9:1 mixture of trans- and cis-fused hydroazulenones 9 and 10.Similarly, cyclization of 7d gives a 31percent yield of 11 with an equatorial methyl group, and cyclization of 8d affor
Perhydroazulenes. 3. Conformations of the 4-Oxoperhydroazulenes
House, Herbert O.,Gaa, Peter C.,VanDerveer, Don
, p. 1661 - 1670 (2007/10/02)
The conformations of cis (1) and trans (2) 4-oxoperhydroazulenes have been studied by employing data from X-ray crystal structures of solid derivatives, 1H NMR spectra, 13C NMR spectra, and molecular mechanics calculations.Related st
