853201-45-3

Upstream product

• 848442-44-4 trifluoromethanesulfonic acid 4-(3-isopropyl-4-methoxymethoxybenzyl)-3,5-dimethylphenyl ester 
• 201230-82-2 carbon monoxide 
• 328236-47-1 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol 

Downstream Products

• 853201-58-8 5-[4-(3-isopropyl-4-methoxymethoxy-benzyl)-3,5-dimethyl-benzyl]-3-methyl-thiazolidine-2,4-dione 
• 853201-57-7 5-(4-(3-isopropyl-4-(methoxymethoxy)benzyl)-3,5-dimethylbenzyl)thiazolidine-2,4-dione 
• 853201-55-5 methyl 2-[4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenyl]-2-hydroxyacetate 

Relevant academic research and scientific papers

Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRβ(R320H): A tailor-made approach toward the treatment of resistance to thyroid hormone

The thyroid hormone receptors (TR) are ligand-dependant transcription factors that regulate key genes involved in metabolic regulation, thermogenesis and development. Resistance to thyroid hormone (RTH) is a genetic disease associated with mutations to TR