853319-87-6

Basic information

• Product Name: 1-(4-bromobenzyl)-3,5,5-trimethyl-4,5-dihydro-1H-pyrazole
• Synonyms: 1-(4-bromobenzyl)-3,5,5-trimethyl-4,5-dihydro-1H-pyrazole
• CAS NO: 853319-87-6
• Molecular Weight: 281.195
• Mol File: 853319-87-6.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-bromobenzyl)-3,5,5-trimethyl-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromobenzyl)-3,5,5-trimethyl-4,5-dihydro-1H-pyrazole(853319-87-6)
• EPA Substance Registry System: 1-(4-bromobenzyl)-3,5,5-trimethyl-4,5-dihydro-1H-pyrazole(853319-87-6)

Safety Data

• Hazardous Substances Data: 853319-87-6(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 21586-21-0 2-methylpentane-2,4-diamine 
• 1308318-18-4 6-(4-bromophenyl)-2,2,4-trimethyl-1,5-diazabicyclo[3.1.0]hexane 
• 103-71-9 phenyl isocyanate 

Relevant articles and documents

Generation of azomethine imines via opening of the diaziridine ring in unsymmetrically substituted 6-aryl-1,5-diazabicyclo-[3.1.0]hexanes and their transformations

Thermally induced opening of the diaziridine ring at the carbon-nitrogen bond in unsymmetrically substituted 6-aryl-1,5-diazabicyclo[3.1.0]hexanes is characterized by low regioselectivity which is likely to be determined by the inductive effect of substituents in the trimethylene bridge. 1,3-Dipolar cycloaddition of the resulting azomethine imines to phenyl isocyanate is regioselective: it occurs at the double carbon-nitrogen bond with predominant formation of the corresponding cis adducts due to dipolarophile approach to Z-azomethine imine at the sterically less hindered side. Analogous approach of dipolarophile is also observed in the reaction with N-arylmaleimides.