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(1S,2S)-2-(4-aminophenyl)cyclopropanecarboxylic acid ethyl ester, also known as Etodolac, is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits potent anti-inflammatory and analgesic properties. It functions by inhibiting the production of prostaglandins, which are responsible for pain and inflammation within the body. Etodolac is a versatile medication that is commonly used to alleviate symptoms associated with various conditions, including osteoarthritis and rheumatoid arthritis.

853404-00-9

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853404-00-9 Usage

Uses

Used in Pharmaceutical Industry:
Etodolac is utilized as an analgesic and anti-inflammatory agent for the treatment of conditions such as osteoarthritis and rheumatoid arthritis. Its ability to reduce pain and inflammation makes it a valuable asset in managing these chronic conditions and improving the quality of life for affected individuals.
Used in Pain Management:
As a nonsteroidal anti-inflammatory drug, Etodolac is employed for pain management in various situations where inflammation and pain are present. It can be used to alleviate discomfort associated with minor injuries, surgeries, or chronic conditions, providing relief and improving overall well-being.
Used in Inflammation Reduction:
Etodolac serves as an effective tool in reducing inflammation throughout the body. By inhibiting the production of prostaglandins, it helps to minimize swelling and associated discomfort, making it a beneficial option for those suffering from inflammatory conditions.
Formulations:
Etodolac is available in various forms, including oral tablets, extended-release tablets, and oral suspensions, allowing for flexible and convenient administration to suit individual patient needs. It is typically taken with food to reduce the risk of stomach upset, further enhancing its usability and tolerability.
Precautions:
While Etodolac offers significant benefits in managing pain and inflammation, it is important to be aware of potential side effects, which may include stomach pain, constipation, diarrhea, and headache. Additionally, there is an increased risk of serious cardiovascular events associated with its use, and as such, it should be used with caution and under the guidance of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 853404-00-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,3,4,0 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 853404-00:
(8*8)+(7*5)+(6*3)+(5*4)+(4*0)+(3*4)+(2*0)+(1*0)=149
149 % 10 = 9
So 853404-00-9 is a valid CAS Registry Number.

853404-00-9Relevant academic research and scientific papers

HETEROCYCLIC UREA COMPOUNDS

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Page/Page column 60, (2013/07/05)

The present invention provides a compound of the following formula, racemates, enantiomers and salts thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture

Synthesis and activity of small molecule GPR40 agonists

Garrido, Dulce M.,Corbett, David F.,Dwornik, Kate A.,Goetz, Aaron S.,Littleton, Thomas R.,McKeown, Steve C.,Mills, Wendy Y.,Smalley Jr., Terrence L.,Briscoe, Celia P.,Peat, Andrew J.

, p. 1840 - 1845 (2007/10/03)

The first report on the identification and structure-activity relationships of a novel series of GPR40 agonists based on a 3-(4-{[N-alkyl]amino}phenyl) propanoic acid template is described. Structural modifications to the original screening hit yielded co

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