85366-66-1

Usage

Uses

Used in Organic Synthesis:
3-Bromo-4-(trifluoromethoxy)benzaldehyde is used as a synthetic intermediate for the production of other complex organic compounds. Its unique structure, featuring a trifluoromethoxy group and a bromine atom, allows for versatile synthetic transformations, making it a valuable component in the synthesis of various organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-bromo-4-(trifluoromethoxy)benzaldehyde is used as a building block for the development of new drugs. Its reactive functional groups can be utilized to create novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
3-Bromo-4-(trifluoromethoxy)benzaldehyde is also employed in chemical research as a model compound to study the reactivity and properties of organobromides and organofluorides. Its unique structure provides insights into the behavior of these functional groups in various chemical reactions and processes.
Used in Material Science:
In the field of material science, 3-bromo-4-(trifluoromethoxy)benzaldehyde can be used as a precursor for the synthesis of new materials with specific properties. Its reactive functional groups can be incorporated into polymers, coatings, or other materials to impart desired characteristics, such as improved stability, enhanced reactivity, or specific binding properties.

InChI:InChI=1/C8H4BrF3O2/c9-6-3-5(4-13)1-2-7(6)14-8(10,11)12/h1-4H

Upstream product

• 659-28-9 p-trifluoromethoxybenzaldehyde 
• 85366-65-0 3-bromo-4-(trifluoromethoxy)benzyl alcohol 

Downstream Products

• 532440-14-5 3-trifluoromethoxy-4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-benzaldehyde 
• 85373-96-2 3-bromo-4-(trifluoromethoxy)benzoic acid 
• 1445565-08-1 (6-bromo-7-trifluoromethoxyisoquinolin-1-yl)tritylamine 
• 1445563-89-2 (2R)-3-(1-amino-7-trifluoromethoxyisoquinolin-6-yl)-2-[(3S)-2-oxo-3-[(2-pyrrolidin-1-ylthiazole-5-sulfonyl)amino]pyrrolidin-1-yl]propionic acid cyclohexyloxycarbonyloxymethyl ester 
• 1445563-86-9 (2R)-3-(1-amino-7-trifluoromethoxyisoquinolin-6-yl)-2-[(3S)-2-oxo-3-[(2-pyrrolidin-1-ylthiazole-5-sulfonyl)amino]pyrrolidin-1-yl]propionic acid 1-cyclohexyloxycarbonyloxyethyl ester 
• 1445564-96-4 (E)-3-(3-bromo-4-trifluoromethoxyphenyl)acrylic acid 
• 1360917-93-6 methyl 4-{8-[3-bromo-4-(trifluoromethoxy)benzyl]-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl}benzoate 
• 500165-19-5 3-(5-isobutyl-3,3-dimethyl-2,3-dihydro-benzofuran-7-yl)-4-trifluoromethoxy-benzaldehyde 
• 532440-89-4 7-[5-formyl-2-trifluoromethoxy-phenyl]-3,3-dimethyl-2,3-dihydro-benzofuran-5-carboxylic acid dimethylamide 
• 1445565-11-6 (2E)-2-[(3S)-3-tert-butoxycarbonylamino-2-oxopyrrolidin-1-yl]-3-[7-trifluoromethoxy-1-(tritylamino)isoquinolin-6-yl]acrylic acid methyl ester 

Relevant academic research and scientific papers

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same. The compounds include an IRAK binding moiety capable of binding to IRAK4 and a degradation inducing moiety (DIM). The DIM could be DTM a ligase binding moiety (LBM) or lysine mimetic. The compounds could be useful as IRAK protein kinase inhibitors and applied to IRAK mediated disorders.

SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

The invention relates to new sulphonylaminopyrrolidinone compounds having antithrombotic activity which, in particular, inhibit blood clotting factor IXa and/ or factor Xa, to processes for their preparation and to use thereof as drugs.

N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases

The present invention relates to certain compounds of Formula (I) which can be useful in the treatment of diseases, such as, cancer, metabolic disorders, Type 2 Diabetes, dyslipidemia and/or hyperchloesterolemia:

Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia

The present invention relates to compounds of Formula (I) which may be useful in the treatment of diseases, such as, metabolic disorders, dyslipidemia and/or hyperchloesterolemia: 1

RXR activating molecules

Disclosed are molecules that activate an RXR receptor, wherein the molecule comprises an RXR binding portion which binds the RXR receptor and comprises a side pocket contacting residue which contacts a side-pocket 1 of an RXR receptor.

Heterocyclic derivatives for the treatment of diabetes and other diseases

The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatoid arthritis, Crohn's Disease or Inflammatory Bowel Disease.

Process for preparing fluorine-containing benzaldehydes

The invention relates to a particularly advantageous preparation of fluorine-containing benzaldehydes by reacting a corresponding aromatic acid chloride with hydrogen in the presence of a supported palladium catalyst and a catalyst moderator.

Combating pests with novel substituted phenylcyclopropanecarboxylic acid esters

Substituted phenyl-cyclopropanecarboxylic acid esters of the formula STR1 in which R1 represents an alkoxy or alkylthio radical which is monosubstituted or polysubstituted by identical or different halogen substituents, R2 represents