85372-19-6

Basic information

• Product Name: 4-methylbenzyl phenyl disulfide
• Synonyms: 4-methylbenzyl phenyl disulfide
• CAS NO: 85372-19-6
• Molecular Weight: 246.397
• Mol File: 85372-19-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-methylbenzyl phenyl disulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylbenzyl phenyl disulfide(85372-19-6)
• EPA Substance Registry System: 4-methylbenzyl phenyl disulfide(85372-19-6)

Safety Data

• Hazardous Substances Data: 85372-19-6(Hazardous Substances Data)

Upstream product

• 18991-39-4 p-methylbenzyl thiocyanate 
• 3111-52-2 potassium thiophenolate 
• 4972-29-6 benzenesulphinyl chloride 
• 4498-99-1 4-methylbenzylthiol 

Relevant articles and documents

Nucleophilic Substitution on 4-Methylbenzyl Thiocyanate with Nucleophiles

The reactions of 4-methylbenzyl thiocyanate (1) with several nucleophiles have been investigated.Compound 1 possesses three electrophilic sites, i.e., benzylic carbon, sulfur and cyano carbon, to receive nucleophilic attack.PhS- and CN- which have HOMO's of high energy levels appear to attack preferentially the sulfur atom.MeO- was found to attack preferably the cyanide carbon, while amines which have HOMO's of low energy levels prefer benzylic carbon to attack.The nucleophilic substitution on the sulfur or the cyanide carbon generates CN- or p-xylene-α-thiolate anion, strong nucleophiles, as the primary products, which then initiate the complex secondary reactions.The selective reactivities of three attacking sites for nucleophiles in 1 have been rationalized in terms of MO theory.