853795-27-4

Basic information

• Product Name: Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxa-6-azaspiro[2.5]oct-6-yl)phenyl]-2-oxo-5-ox azolidinyl]methyl]-
• CAS NO: 853795-27-4
• Molecular Formula: C18H22FN3O4
• Molecular Weight: 363.389
• Mol File: 853795-27-4.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxa-6-azaspiro[2.5]oct-6-yl)phenyl]-2-oxo-5-ox azolidinyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxa-6-azaspiro[2.5]oct-6-yl)phenyl]-2-oxo-5-ox azolidinyl]methyl]-(853795-27-4)
• EPA Substance Registry System: Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxa-6-azaspiro[2.5]oct-6-yl)phenyl]-2-oxo-5-ox azolidinyl]methyl]-(853795-27-4)

Safety Data

• Hazardous Substances Data: 853795-27-4(Hazardous Substances Data)

Upstream product

• 1774-47-6 trimethylsulfoxonium iodide 
• 172966-53-9 (S)-N-{3-[3-fluoro-4-(4-oxo-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 

Downstream Products

• 1188330-38-2 (S)-N-(3-{4-[4-(2-bromo-4-nitro-imidazol-1-ylmethyl)4-hydroxy-piperidin-1-yl]-3-fluoro-phenyl}-2-oxo-oxazolidin-5-ylmethyl)-acetamide 
• 1188917-88-5 (S)-N-{3-[4-(6-nitro-imidazo[2,1-b]-2(3H)-8-aza-spiro[4.5]dec-8-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 853795-19-4 (S)-N-{3-[4-(4-fluoro-4-aminomethylpiperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 

Relevant articles and documents

BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES

The current invention provides a series of bicyclic nitroimidazole- substituted phenyl oxazolidinones in which a bicyclic nitroimidazole pharmacophore is covalently bonded to a phenyl oxazolidinone, their pharmaceutical compositions, and the method of use of the compositions for prevention and treatment of bacterial infections. The bicyclic nitroimidazole-substituted phenyl oxazolidinones possess surprising antibacterial activity against wild- type and resistant strains of pathogens, and are therefore useful for the prevention, control and treatment of a number of human and veterinary bacterial infections caused by these pathogens, such as Mycobacterium tuberculosis.