853799-40-3Relevant academic research and scientific papers
Synthesis of glycaro-1,5-lactams and tetrahydrotetrazolopyridine-5- carboxylates: Inhibitors of β-D-glucuronidase and α-L-iduronidase
Pabba, Jagadish,Rempel, Brian P.,Withers, Stephen G.,Vasella, Andrea
, p. 635 - 666 (2007/10/03)
The known glucaro-1,5-lactam 8, its diastereoisomers 9-11, and the tetrahydrotetrazolopyridine-5-carboxylates 12-14 were synthesised as potential inhibitors of β-D-glucuronidases and α-L-iduronidases. The known 2,3-di-O-benzyl-4,6-O-benzylidene-D-galactos
Synthesis of D-gluco-, L-ido-, D-galacto-, and L-altro-configured glycaro-1,5-lactams from tartaric acid
Pabba, Jagadish,Vasella, Andrea
, p. 3619 - 3622 (2007/10/03)
The D-gluco-, L-ido-, D-galacto-, and L-altro-configured glycaro-1,5-lactams 1-4 were prepared from the known tartaric anhydride 5 via the aldehyde 6. These lactams are known (1) or potential (2-4) inhibitors of β-D-glucuronidases and α-L-iduronidases. Ol
