85382-75-8Relevant academic research and scientific papers
Controlled reduction of acarbose: Conformational analysis of acarbose and the resulting saturated products
Bock,Meldal,Refn
, p. 1 - 16 (2007/10/02)
Saturation of the double bond in the non-reducing terminal unit of the tetrasaccharide amylase inhibitor, acarbose (1), with Raney nickel as the catalyst and at pH 8, gave 57% of a ~1:1 mixture of the 5a-carba-gluco (2) and -ido (3) isomers together with
Synthesis of "dihydroacarbose", an α-d-glucosidase inhibitor having a pseudo-tetrasaccharide structure
Hayashida, Mitsuo,Sakairi, Nobuo,Kuzuhara, Hiroyoshi,Yajima, Motoyuki
, p. 233 - 246 (2007/10/02)
"Dihydroacarbose" (2), an α-d-glucosidase inhibitor having a pseudo-tetrasaccharide structure, was synthesized by reductive coupling of 43-amino-11,61-anhydro-21,31,22,32,62
UNTERSUCHUNGEN ZUR STRUCTUR DES α-D-GLUCOSIDASEINHIBITORS ACARBOSE
Junge, Bodo,Heiker, Fred-R.,Kurz, Juergen,Mueller, Lutz,Schmidt,Delf D.,Wuensche, Christian
, p. 235 - 268 (2007/10/02)
Hydrolysis of the pseudotetrasaccharide acarbose (1), a potent inhibitor of intestinal α-D-glucosidases and effective oral antidiabetic agent, gave D-glucose and a tricyclic compound (1R,2S,3R,4aS,7R,8S,8aS,9aR)-1,2,3,4a,7,8,8a,9a-octahydro-1,2,7,8-tetrah
