85392-02-5Relevant academic research and scientific papers
Synthesis of new arylethanolamine and aryloxypropanolamine derivatives including 1,4-benzodioxine moiety
Boye, Sophie,Guillaumet, Gerald,Viaud, Marie-Claude
, p. 537 - 554 (2007/10/03)
The synthesis of new arylethanolamines and aryloxypropanolamines variously substituted on the nitrogen atom are described. Access to these compounds, which are potential β3-adrenergic ligands, involves, as key step, a reductive amination reaction between 2-amino alcohols and 1,4-benzodioxine aldehyde derivatives.
THIOCHROMAN COMPOUNDS
-
, (2008/06/13)
The invention relates to compounds of the formula I: STR1 in which R 1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.
THIOCHROMAN COMPOUNDS
-
, (2008/06/13)
(3-amino-2-hydroxy propyloxy) thiochromans of the formula SPC1Wherein A is hydrogen or halogen, R 1 is hydrogen or lower alkyl, and R 2 is lower alkyl or cyclo lower alkyl. These compounds possess cardiovascular properties and may be used as blockers of cardiac β adrenergic receptors.
