853941-38-5Relevant academic research and scientific papers
RNA duplexes with biphenyl substituents as base replacements are less stable than DNA duplexes
Brotschi, Christine,Leumann, Christian J.
, p. 2023 - 2025 (2005)
Introduction of a hydrophobic biphenyl-C-nucleotide pair into a 11-mer RNA duplex is associated with a net penalty in the free energy of duplex formation of 2.0 kcal mol-1 or 10 °C in Tm, relative to DNA. These differential stabiliti
