854015-61-5

Basic information

• Product Name: (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL
• Synonyms: (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL;4-iodo-5-methyl-3-Isoxazolemethanol
• CAS NO: 854015-61-5
• Molecular Formula: C₅H₆INO₂
• Molecular Weight: 239.01111
• EINECS: -0
• Mol File: 854015-61-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL(854015-61-5)
• EPA Substance Registry System: (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL(854015-61-5)

Safety Data

• Hazardous Substances Data: 854015-61-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
(4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL is used as an active pharmaceutical ingredient for its antimicrobial and anti-inflammatory properties, which can be harnessed to develop new drugs targeting various infections and inflammation-related conditions.
Used in Organic Synthesis:
(4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL is used as a key intermediate in the synthesis of various bioactive compounds, playing a crucial role in drug discovery and development. Its unique structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Laboratory Research:
(4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL is used as a reagent in laboratories for conducting various chemical reactions, contributing to the advancement of chemical knowledge and the development of new chemical processes and compounds.
Used in Antimicrobial Applications:
In the medical industry, (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL is used as an antimicrobial agent for its ability to combat various types of infections, making it a valuable tool in the development of new antibiotics and antifungal agents.
Used in Anti-inflammatory Applications:
In the pharmaceutical industry, (4-IODO-5-METHYL-1,2-OXAZOL-3-YL)METHANOL is used as an anti-inflammatory agent, potentially leading to the development of new treatments for conditions characterized by chronic inflammation, such as arthritis and autoimmune diseases.

Upstream product

• 35166-33-7 (5-methyl-isoxazol-3-yl)-methanol 

Downstream Products

• 1616402-06-2 3-amino-1-(4-chlorobenzyl)-5-(3-(hydroxymethyl)-5-methylisoxazol-4-yl)pyridin-2(1H)-one 
• 1616401-90-1 3-amino-1-benzyl-5-(3-(hydroxymethyl)-5-methylisoxazol-4-yl)pyridin-2(1H)-one 
• 1257875-23-2 [5-methyl-4-(6-{4-[(trifluoromethyl)oxy]phenyl}-3-pyridinyl)-3-isoxazolyl]methanol 

Relevant articles and documents

Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin

Carbon monoxide (CO) poisoning causes between 5,000-6,000 deaths per year in the US alone. The development of small molecule allosteric effectors of CO binding to hemoglobin (Hb) represents an important step toward making effective therapies for CO poison

Isoxazole mediated synthesis of 4-(1H)pyridones: Improved preparation of antimalarial candidate GSK932121

A new synthesis of the antimalarial clinical candidate GSK932121 is described. This approach has two key reactions, the selective acylation of an unprotected 3-hydroxymethyl-5-methyl isoxazole and the reductive N-O bond cleavage of the previously function

BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS

This application relates to chemical compounds which may act as inhibitors of; or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2, R2b, R3, R4a, R4b, and R5 are described herein.

ISOXAZOLE DERIVATIVE HAVING AGONISTIC ACTIVITY AGAINST PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR

A compound of formula (I) : (wherein R1-R10 are each independently hydrogen, halogen, optionally substituted lower alkyl or the like, X1 is -O-, -S-, -NR11- (wherein R11 is hydrogen, lower alkyl or the like), -CR12R13CO-, -(CR12R13)mO-, -O(CR12R13)m- (wherein R12 and R13 are each independently hydrogen or lower alkyl and m is a integer between 1 and 3) or the like, X2 is a bond, -O-, -S-, -NR14- (wherein R14 is hydrogen, lower alkyl or the like, R14 and R6 can be taken together with the neighboring atom to form a ring) or -CR15R16-(wherein R15 and R16 are each independently hydrogen or lower alkyl, R15 and R6 or R10 can be taken together with the neighboring carbon atom to form a ring, R16 and R9 can be joined together to form a bond), X3 is COOR17, C( = NR17)NR18OR19 or the like), a pharmaceutically acceptable salt or a solvate thereof.