854036-30-9Relevant academic research and scientific papers
Atom-economic, solvent-free, high yield synthesis of 2-(pyrrol-1-yl) propyldiorganylphosphines
Trofimov, Boris A.,Gusarova, Nina K.,Sukhov, Boris G.,Malysheva, Svetlana F.,Tarasova, Olga A.,Belogorlova, Natalya A.,Maximova, Marina A.,Tunik, Sergey P.
, p. 965 - 970 (2005)
Free-radical addition of secondary phosphines to 1-isopropenylpyrroles (AIBN, 65°C) proceeds with 100% regioselectivity to give 2-(pyrrol-1-yl)propyldiorganylphosphines in 89-92% isolated yields. This constitutes a highly efficient, atom-economic, solvent-free ('green') synthesis of new promising ligands for metal complex catalysts, and potent building blocks for designing of drugs and advanced materials. Georg Thieme Verlag Stuttgart.
