854137-57-8

Basic information

• Product Name: 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylic acid
• Synonyms: 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylic acid
• CAS NO: 854137-57-8
• Molecular Weight: 253.709
• Mol File: 854137-57-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylic acid(854137-57-8)
• EPA Substance Registry System: 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylic acid(854137-57-8)

Safety Data

• Hazardous Substances Data: 854137-57-8(Hazardous Substances Data)

Upstream product

• 186000-42-0 (3-chlorophenyl)zinc(II) iodide 
• 1160573-81-8 ethyl 2-(3-chlorophenyl)-4-methylthiazole-5-carboxylate 

Downstream Products

• 1354948-44-9 C₂₃H₂₂ClN₃O₃S 

Relevant articles and documents

CHEMICAL COMPOUNDS

A compound of formula (I), wherein Ar1, R21, R23, R24, R25, R26, R27, A, X, Y and W are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.