85421-89-2

Usage

InChI:InChI=1/C11H15N5O5/c1-3(17)7-5(18)6(19)10(21-7)16-2-13-4-8(16)14-11(12)15-9(4)20/h2-3,5-7,10,17-19H,1H3,(H3,12,14,15,20)

Upstream product

• 85421-83-6 9-<6'-deoxy-2',3',5',-tris-O-(p-nitrobenzoyl)-β-D-allofuranosyl>-N²-acetylguanine 
• 54187-52-9 O,9-bis(trimethylsilyl)-N²-acetylguanine 
• 85505-01-7 6-deoxy-2,3,5-tris-O-(p-nitrobenzoyl)-D-allofuranosyl bromide 
• 1246254-48-7 1-(2-amino-6-chloropurin-N9-yl)-5(R)-C-methyl-β-D-ribofuranose 

Relevant academic research and scientific papers

SUBSTITUTED NUCLEOTIDE ANALOGS

Disclosed herein are phosphoroamidate nucleotide analogs, methods of synthesizing phosphoroamidate nucleotide analogs and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with the phosphoroamidate

SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS

Disclosed herein are nucleotide analogs with protected phosphates, methods of synthesizing nucleotide analogs with protected phosphates and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with the nucleotide analogs with protected phosphates.

Synthesis of hypoxanthine, guanine, and 6-thiopurine nucleosides of 6-deoxy-D-allofuranose

Hypoxanthine, guanine, and 6-thiopurine nucleosides of 6-deoxy-D-allofuranose have been prepared as potential antitumor agents. Thus, reaction of 6-deoxy-β-allofuranosyl bromide (1) with the trimethylsilyl derivatives of hypoxanthine and guanine afforded