854259-26-0Relevant academic research and scientific papers
Synthesis of substituted benzoxacycles via a domino ortho-alkylation/heck coupling sequence
Martins, Andrew,Marquardt, Udo,Kasravi, Neema,Alberico, Dino,Lautens, Mark
, p. 4937 - 4942 (2007/10/03)
The synthesis of a variety of alkylidene benzoxacycles via a domino palladium-catalyzed ortho-alkylation/intramolecular Heck reaction is described. Under the optimized conditions [Pd(OAc)2 (10 mol %), P(2-Furyl) 3 (20 mol %), norborn
Sequential hydrostannylation-cyclisation of δ- and ω-allenyl aryl halides. Cyclisation at the proximal carbon
Grigg, Ronald,Sansano, Jose M.
, p. 13441 - 13454 (2007/10/03)
Palladium catalysed hydrostannylation of (Bu3SnH, THF, O°C) of δ- and ω-allenyl aryl halides followed by mono- or bis-cyclisation (MeCN, 80°C) affords small (5-7), large (11-17) and spirocyclic rings in which cyclisation occurs at the proximal
