854428-57-2

Basic information

• Product Name: N-phenyl-2-chlorobutanamide
• Synonyms: N-phenyl-2-chlorobutanamide
• CAS NO: 854428-57-2
• Molecular Weight: 197.664
• Mol File: 854428-57-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyl-2-chlorobutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-chlorobutanamide(854428-57-2)
• EPA Substance Registry System: N-phenyl-2-chlorobutanamide(854428-57-2)

Safety Data

• Hazardous Substances Data: 854428-57-2(Hazardous Substances Data)

Upstream product

• 21486-48-6 2-bromo-N-phenylbutanamide 
• 62-53-3 aniline 

Downstream Products

• 1418645-64-3 C₄₁H₃₆N₂O*C₁₀H₁₂ClNO 
• 131859-66-0 2-(4-Hydroxy-6-methoxy-2,2-dimethyl-chroman-7-yloxy)-N-phenyl-butyramide 
• 131859-64-8 2-(4-Hydroxy-2,2-dimethyl-chroman-7-yloxy)-N-phenyl-butyramide 
• 131859-70-6 2-(6-Methoxy-2,2-dimethyl-2H-chromen-7-yloxy)-N-phenyl-butyramide 
• 131859-68-2 2-(2,2-Dimethyl-2H-chromen-7-yloxy)-N-phenyl-butyramide 
• 131859-60-4 2-(2,2-Dimethyl-4-oxo-chroman-7-yloxy)-N-phenyl-butyramide 
• 131859-62-6 2-(6-Methoxy-2,2-dimethyl-4-oxo-chroman-7-yloxy)-N-phenyl-butyramide 

Relevant articles and documents

Dichloromethane as a chlorination reagent for α-bromocarbonyl compounds in the presence of a copper catalyst

We found that dichloromethane is a powerful chlorinating reagent for the congested 3° and 2° Csp3Br bond of α-bromocarbonyl amides, esters, and ketones. In the presence of an appropriate copper complex as a catalyst, the desired chlorination occurred within an hour. Control experiments revealed that in situ-generated CuCl2 is a key chlorinating agent that reacts with the 3° or 2° alkyl radicals generated by the reaction between an α-bromocarbonyl compound and a Cu(I) salt.