854481-65-5 Usage
Molecular structure
A steroid backbone with multiple functional groups attached, including t-butyldimethylsilyloxy and 3-oxobutyloxy groups.
Origin
A derivative of pregnene, a naturally occurring steroid hormone.
Field of use
Commonly used in the field of organic chemistry.
Reactivity
Unique reactivity due to the presence of t-butyldimethylsilyloxy and 3-oxobutyloxy groups, making it useful in various chemical reactions and synthetic processes.
Potential applications
Pharmaceutical and medicinal chemistry, particularly in the synthesis of hormone-based drugs and research on steroid biochemistry.
Value
A valuable and versatile compound in organic chemistry with diverse potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 854481-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,4,8 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 854481-65:
(8*8)+(7*5)+(6*4)+(5*4)+(4*8)+(3*1)+(2*6)+(1*5)=195
195 % 10 = 5
So 854481-65-5 is a valid CAS Registry Number.
854481-65-5Relevant articles and documents
Industrial synthesis of maxacalcitol, the antihyperparathyroidism and antipsoriatic vitamin D3 analogue exhibiting low calcemic activity
Shimizu, Hitoshi,Shimizu, Kazuki,Kubodera, Noboru,Mikami, Tetsuhiro,Tsuzaki, Kaname,Suwa, Hiroyuki,Harada, Koji,Hiraide, Akira,Shimizu, Motoki,Koyama, Kaichiro,Ichikawa, Yoshihide,Hirasawa, Daisuke,Kito, Yasushi,Kobayashi, Mio,Kigawa, Masaharu,Kato, Masahiro,Kozono, Toshiro,Tanaka, Hideki,Tanabe, Makoto,Iguchi, Masanori,Yoshida, Mitsutaka
, p. 278 - 287 (2005)
Maxacalcitol, the 22-oxa-derivative of 1α,25-dihydroxyvitamin D 3 and used currently as an antihyperparathyroidism and antipsoriatic drug, has been synthesized in seven chemical steps from 1α- hydroxydehydroepiandrosterone on the basis of our previously developed route. The present synthesis allows the production of the protected form of the penultimate intermediate in 26% overall yield in a kilogram scale reaction employing neither difficult reaction conditions nor chromatographic purification, having overcome all the difficulties involved in the previous route.
