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Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 343338-28-3 (S)-2-methylpropane-2-sulfinamide 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure aryl, hetero aryl and alkyl sulfinimides catalyzed by recyclable tungstophosphoric acid

A simple and efficient procedure was developed for the preparation of a variety of aryl, hetero aryl and alkyl N-sulfinylimines (2b-2u) with excellent yields (85–94%) using tungstophosphoric acid as catalyst. Also, this new synthetic protocol features hig

Additive effects in the palladium-catalyzed carboiodination of chiral N-allyl carboxamides

The use of Pd catalysis as a means to synthesize organic halides has recently received increased attention. Among the reported methods is the Pd-catalyzed carboiodination, which uses extremely bulky ligands to facilitate carbon-halogen reductive eliminati

Diastereoselective Pomeranz-Fritsch-Bobbitt synthesis of (S)-(-)-O-methylbharatamine using (S)-N-tert-butanesulfinimine as a substrate

The protoberberine-type alkaloid, (S)-(-)-O-methylbharatamine, has been synthesized in six steps involving the addition of laterally lithiated o-toluamide to (S)-N-tert-butanesulfinimine as the crucial process. The target alkaloid was obtained in 24.4% overall yield with 88% ee.

KHSO4-mediated condensation reactions of tert-butanesulfinamide with aldehydes. Preparation of tert-butanesulfinyl aldimines

Optically pure tert-butanesulfinyl aldimines 1 were prepared by direct condensation of chiral tert-butanesulfinamide 3 with aldehydes 2 in high yields in the presence of KHSO4. The main advantage of KHSO4 is that it is applicable to the condensation reactions of a variety of aldehydes, including electron deficient and electron rich (hetereo)aromatic aldehydes, as well as aliphatic aldehydes.