85451-50-9Relevant academic research and scientific papers
Synthesis and biological activities of 5-substituted 6-phenylthio and 6-iodouridines, a new class of antileukemic nucleosides
Tanaka,Matsuda,Iijima,Hayakawa,Miyasaka
, p. 2164 - 2167 (2007/10/02)
A new class of 5,6-disubstituted uridines, in which the C-6 position was occupied by phenylthio group or iodine, were synthesized via lithiation of the corresponding 5-substituted 2',3'-O-isopropylidene-5'-O-methoxymethyl-uridines and subsequent electroph
"UMPOLUNG" OF REACTIVITY AT THE C-6 POSITION OF URIDINE: A SIMPLE AND GENERAL METHOD FOR 6-SUBSTITUTED URIDINES
Tanaka, Hiromichi,Hayakawa, Hiroyuki,Miyasaka, Tadashi
, p. 2635 - 2642 (2007/10/02)
Lithiated 2',3'-O-isopropylidene-5'-O-methoxymethyl-uridine was found to react with a variety of electrophilic reagents regiospecifically at the C-6 position.The protecting groups of the ribose moiety in the 6-functionalized products were concurrently rem
