85459-97-8

Upstream product

• 98-01-1 furfural 
• 108-26-9 3-methyl-2-pyrazoline-5-one 
• 109-77-3 malononitrile 
• 141-97-9 ethyl acetoacetate 
• 3237-22-7 2-cyano-3-(2-furanyl)acrylonitrile 
• 79785-97-0 hydrazine hydrate 
• 7803-57-8 hydrazine hydrate 
• 99941-44-3 4-[1-Furan-2-yl-meth-(E)-ylidene]-5-methyl-2,4-dihydro-pyrazol-3-one 
• 99941-44-3 4-furfurylidene-3-methyl-5-oxo-4,5-dihydropyrazole 

Relevant academic research and scientific papers

One-pot synthesis of 2-amino-3-cyano-4H-pyrans and pyran-annulated heterocycles using sodium citrate as an organo-salt based catalyst in aqueous ethanol

Sodium citrate as a highly efficient catalyst is developed for the synthesis of functionalized 2-amino-3-cyano-4H-pyrans and pyran-annulated heterocycles. This method involves a one-pot three-component reaction of aromatic aldehydes, malononitrile and 1,3

Sugarcane Bagasse Ash-Based Silica-Supported Boric Acid (SBA-SiO2-H3BO3): A Versatile and Reusable Catalyst for the Synthesis of 1,4Dihydropyrano[2,3c]pyrazole Derivatives

Abstract: A simple, green, and efficient protocol has been developed for the synthesis of biologically active 1,4dihydropyrano[2,3c]pyrazole derivatives via one-pot four-component reaction of various substituted benzaldehydes, hydrazine hydrate or phenylh

Concentrated solar radiation-assisted one-pot/multicomponent synthesis of pyranopyrazole derivatives under neat condition

Concentrated solar radiation (CSR)-assisted synthesis of pyranopyrazole derivatives under solvent and catalyst-free condition has been reported in the present protocol. One-pot multicomponent synthesis from aromatic/heteroaldehyde, ethyl acetoacetate, malononitrile, and hydrazine hydrate leads to the final desired compounds in a good yield. This operationally simple methodology has several advantages such as green and clean reaction profile, simple workup and purification procedures, extremely short reaction time, atom efficiency, and being economical. The current energy-efficient method saves almost 98% of energy as compared to the conventional method. Graphical abstract: [Figure not available: see fulltext.]

An expedient and eco-friendly approach for multicomponent synthesis of dihydropyrano[2,3-c]pyrazoles using nano-Al2O3/BF3/Fe3O4 as reusable catalyst

The pyranopyrazole derivatives have many biological activities. They were synthesized via a four-component coupling of aromatic aldehyde, malononitrile, ethyl acetoacetate and hydrazine hydrate. In this study, dihydropyrano[2,3-c]pyrazoles have been synth

Green synthesis of pyrazolopyranopyrimidinone and pyranopyrazole derivatives using porphyrin-initiated amine-functionalized PolyBCMO dendritic polymer as sonocatalyst

A novel porphyrin-initiated amine-functionalized poly-3,3-bis(chloromethyl)oxetane (PBCMO-amine) dendritic polymer was effectively synthesized. Characterization using the UV-vis, IR, NMR, PXRD, TG, and FE-SEM spectroscopy and microscopy enabled one to ass

Catalyst-free green synthesis of dihydropyrano[2,3-c]pyrazole scaffolds assisted by ethylene glycol (E-G) as a reusable and biodegradable solvent medium

Abstract: We revealed a catalyst-free, green and rapid one-pot four-component tandem strategy for the preparation of dihydropyrano[2,3-c]pyrazoles – a biologically significant scaffold – via Knoevenagel-Michael cyclocondensation based on green chemistry p

Design and development of a new functionalized cellulose-based magnetic nanocomposite: preparation, characterization, and catalytic application in the synthesis of diverse pyrano[2,3-c]pyrazole derivatives

In this work, a facile protocol for the preparation of a new cellulose-based functionalized magnetic nanocomposite catalyst is described. The structure and morphology of the prepared nanomaterial was characterized by scanning electron microscopy, energy-d

Natural Phosphate K09 as a New Reusable Catalyst for the Synthesis of Dihydropyrano[2,3-c]Pyrazole Derivatives at Room Temperature

Abstract: In this study, we report a simple, efficient and green protocol for the synthesis of pyrano[2,3-c]pyrazole derivatives by the use of the natural phosphate K09 as a mild and efficient heterogeneous catalyst. The catalytic efficiency of K09 was compared with other heterogeneous catalysts to determine the best catalyst for said conversion. Easy recovery of the catalyst and its reusability, room temperature reaction conditions, short reaction time, excellent yields, are some of the important features of this protocol.

Core-shell structured magnetic silica supported propylamine/molybdate complexes: An efficient and magnetically recoverable nanocatalyst

In the present study, a novel core-shell structured magnetic silica supported propylamine/molybdate complex (Fe3O4@SiO2/Pr-NMo[Mo5O18]) is prepared, characterized and applied as an effective and easil