854602-80-5

Upstream product

• 2863-98-1 4-hydrazinobenzonitrile hydrochloride 
• 75052-04-9 2-isothiocyanato-1,1-dimethoxyethane 

Downstream Products

• 1472068-49-7 4-{[4-(benzyloxy)-2-fluorobenzyl](1H-imidazol-1-yl)amino}benzonitrile 
• 1472068-50-0 4-[(2-fluoro-4-hydroxybenzyl)(1H-imidazol-1-yl)amino]benzonitrile 
• 1472067-99-4 4-{[(4-cyanophenyl)(1H-imidazol-1-yl)amino]methyl}-3-fluorophenylsulfamate 

Relevant academic research and scientific papers

Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate

4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate and its ortho-halogenated (F, Cl, Br) derivatives are first-generation dual aromatase and sulfatase inhibitors (DASIs). Structure-activity relationship studies were performed on these

1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them

The invention relates to the compounds of formula (I): In which R1, R2, R3, R4, R5, R6, m and n are as defined in the specification, which are potent aromatase and/or steroid sulfatase and/