854671-69-5

Usage

Uses

Used in Chemical Synthesis:
2,4-Dimethyl-3,5-dinitrobenzoic acid is used as an intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities and materials.
Used in Agriculture as a Herbicide:
In the agricultural industry, 2,4-Dimethyl-3,5-dinitrobenzoic acid is used as a selective herbicide for controlling a broad range of broadleaf weeds in different crops and non-crop areas. It functions by disrupting the growth of the plants, and is typically applied as a spray or in liquid formulation.
Safety Considerations:
It is crucial to handle 2,4-Dimethyl-3,5-dinitrobenzoic acid with care due to its potential toxicity if ingested or inhaled, as well as its ability to cause skin and eye irritation. Proper safety measures should be taken during its application and handling to minimize risks.

Upstream product

• 611-01-8 2,4-dimethyl-benzoic acid 
• 108-38-3 m-xylene 

Relevant academic research and scientific papers

Formation of dihydronaphthalenes via organocatalytic enatioselective michael-aldol cascade reactions with arylalkanes

An organocatalytic highly enantioselective Michael-aldol cascade access to valuable chiral dihydronaphthalenes has been realized. Notably, the strategy via activation of nucleophilic alkyl chains by introducing nitro, chloro, or CF3 group(s) at the ortho- and/or para-position(s) on an aromatic ring renders them readily deprotonated to produce highly reactive nulecophilic species in the cascade process under mild conditions.

Synthesis and reactivity with β-lactamases of 'penicillin-like' cyclic depsipeptides

Several 7-carboxy-3-amido-3,4-dihydro-2H-1-benzopyran-2-ones have been synthesized as potential β-lactamase substrates and/or mechanism-based inhibitors. Substituted o-tyrosine precursors were prepared by the Sorensen method and then heated in vacuo to give the lactones. These compounds are cyclic analogues of aryl phenaceturates which are known to be β-lactamase substrates. The goal of incorporating the scissile ester group into a lactone was to retain the leaving group tethered to the acyl moiety at the acyl- enzyme stage of turnover by serine β-lactamases, in a manner similar to that during penicillin turnover. Further, in two cases, a functionalized methylene group para to the leaving group phenoxide oxygen was incorporated. These molecules possess a latent p-quinone methide electrophile which could, in principle, be unmasked during enzymic turnover and react with an active site nucleophile. All of these compounds were found to be substrates of class A and C β-lactamases, the first δ-lactones with such activity. Generally, k(cat) values were smaller than for the analogous acyclic depsipeptides, which suggests that the tethered leaving group may obstruct the attack of water on the acyl-enzymes. Further exploration of this structural theme might lead to quite inert acyl-enzymes and thus to significant inhibitors. Despite the apparent advantage offered by the longer-lived acyl-enzymes, the functionalized compounds were no better as irreversible inhibitors than comparable acyclic compounds [Cabaret, D.; Liu, J.; Wakselman, M.; Pratt, R. F.; Xu, Y. Bioorg. Med. Chem. 1994, 2, 757-771]. Thus, even tethered quinone methides, at least when placed as dictated by the structures of the present compounds, were unable to efficiently trap a nucleophile at serine β- lactamase active sites.

Process for the production of nitro derivatives of aromatic compounds

Nitroderivates of aromatic compounds which are difficult to nitrate, can readily be obtained by nitration providing that the aromatic compound is treated with nitric acid or another nitrating agent in the presence of aliphatic or cycloaliphatic hydrocarbons monosubstituted or polysubstituted by halogen, the nitro group or an alkyl sulphonyl group, and the nitro derivative formed subsequently isolated.