85468-38-8 Usage
Uses
Used in Pharmaceutical Industry:
2-Hydroxy-3-(aminomethyl)pyridine hydrochloride is used as a key intermediate in the synthesis of dihydroindenyl piperazinediones, which are Oxytocin receptor antagonists. These antagonists are valuable for the treatment of various gynecological conditions, such as dysmenorrhea, pre-term labor, and endometriosis. By targeting the Oxytocin receptors, these antagonists help regulate the hormonal balance and alleviate the symptoms associated with these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 85468-38-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,4,6 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85468-38:
(7*8)+(6*5)+(5*4)+(4*6)+(3*8)+(2*3)+(1*8)=168
168 % 10 = 8
So 85468-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O.ClH/c7-4-5-2-1-3-8-6(5)9;/h1-3H,4,7H2,(H,8,9);1H
85468-38-8Relevant articles and documents
Reaction of N-(2-Pyridylmethyl)-3,5-dimethylbenzamide and N-(3-Pyridylmethyl)-3,5-dimethylbenzamide N-Oxides with Acetic Anhydride
Brana, Miguel F.,Rodriguez, Maria Luz Lopez
, p. 1297 - 1300 (2007/10/02)
As a continuation of our work on the reaction of N-pyridylmethyl-3,5-dimethylbenzamide N-oxides with acetic anhydride, we now report a study of the reaction of N-(2-pyridylmethyl)-3,5-dimethylbenzamide N-oxide (5) and N-(3-pyridylmethyl)-3,5-dimethylbenzamide N-oxide (6) with acetic anhydride.Compound 5 gave N,N'-di(3,5-dimethylbenzoyl)-1,2-di(2-pyridyl)ethenediamine (7) and 3,5-dimethylbenzamide (8).Compound 6 afforded three products formulated as 2-acetoxy-3-(3,5-dimethylbenzoylaminomethyl)pyridine (12), 3-(3,5-dimethylbenzoylaminomethyl)-2-pyridone (13) and 5-(3,5-dimethylbenzoylaminomethyl)-2-pyridone (14).Analytical and spectral data are presented which support the structures proposed.
