854699-16-4

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 5-formyl-
• CAS NO: 854699-16-4
• Molecular Formula: C5H4N2O3
• Molecular Weight: 140.098
• Mol File: 854699-16-4.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 5-formyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 5-formyl-(854699-16-4)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 5-formyl-(854699-16-4)

Safety Data

• Hazardous Substances Data: 854699-16-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazole-3-carboxylic acid, 5-formylis used as a building block for the synthesis of pharmaceutical compounds due to its versatile chemical structure and potential biological activities. Its presence in the pyrazole family suggests that it may contribute to the development of new drugs with therapeutic applications.
Used in Agrochemical Industry:
1H-Pyrazole-3-carboxylic acid, 5-formylis used as a component in the formulation of agrochemicals, such as pesticides and herbicides. 1H-Pyrazole-3-carboxylic acid, 5-formyl-'s chemical properties may enable the creation of novel agrochemicals with improved efficacy and reduced environmental impact.
Used in Dye Industry:
1H-Pyrazole-3-carboxylic acid, 5-formylis used as a precursor in the synthesis of dyes, particularly those with specific color properties and stability. 1H-Pyrazole-3-carboxylic acid, 5-formyl-'s aromatic nature and functional groups may contribute to the development of new dyes with enhanced performance characteristics.
Used in Materials Science:
1H-Pyrazole-3-carboxylic acid, 5-formylis used as a component in the development of new materials with unique properties, such as high thermal stability, electrical conductivity, or optical properties. 1H-Pyrazole-3-carboxylic acid, 5-formyl-'s heterocyclic structure and functional groups may play a crucial role in the design and synthesis of advanced materials for various applications.

Upstream product

• 93290-12-1 ethyl 3⁽⁵⁾-formylpyrazole-5⁽³⁾-carboxylate 
• 840504-43-0 5-dimethoxymethyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 107518-34-3 5-formyl-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester 

Downstream Products

• 925687-36-1 3-(4,4,5,5-tetramethyl-3-oxido-1-oxyl-4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole-5-carboxylic acid 

Relevant articles and documents

NOVEL PHARMACEUTICAL COMPRISING HETEROAROMATIC AMIDE DERIVATIVE OR SALT THEREOF

PROBLEM TO BE SOLVED: To provide a compound useful for treating or preventing disease associated with voltage-dependent sodium channel (Nav1.7) such as disease involving a pain, disease involving an itch, autonomic nerve-associated disease, or a pharmaceutical composition thereof. SOLUTION: The present disclosure provides a compound illustrated by the following formula, and a pharmaceutical composition containing the same. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME

A compound selectively inhibiting Nav1.7 over Nav1.5 is provided. A heteroaromatic amide derivative or salt thereof showing high efficacy for various diseases associated with Nav1.7 such as pain, represented by the general formula (I) [wherein, X1-X2 is N-C or C-N, Y1 , Y2, Y3 and Y4 are -CH2-, -CR4aH- or -O- and so on, Z1 is-O- and so on, ring A is a 3- to 7-membered monocyclic aromatic ring and so on, R1a and R1b are a hydrogen atom or a halogen atom and so on, R2 is a hydrogen atom and so on, R3a, R3b and R3c are a hydrogen atom or an optionally substituted C1-C6 haloalkyl group and so on, R4a, R4b and R4c are, an optionally substituted C1-C6 haloalkyl group or C1-C6 haloalkoxy group and so on, R5a is a hydrogen atom and so on, R5a and R5b together form -CH2O- and so on, R6a and R6b are a hydrogen atom and so on, n is 1 or 2.].

1,3-Dipolar cycloaddition in the synthesis of pyrazolyl-substituted nitronyl nitroxides

A new approach to the synthesis of polyfunctional pyrazolyl-substituted nitronyl nitroxides was developed based on the presynthesized pyrazole derivatives prepared by 1,3-dipolar cycloaddition. The structures of the resulting mono- and biradicals were confirmed by X-ray diffraction.