854777-63-2Relevant academic research and scientific papers
4-(3-Aryloxyaryl)quinoline alcohols are liver X receptor agonists
Bernotas, Ronald C.,Kaufman, David H.,Singhaus, Robert R.,Ullrich, John,Unwalla, Rayomand,Quinet, Elaine,Nambi, Ponnal,Wilhelmsson, Anna,Goos-Nilsson, Annika,Wrobel, Jay
experimental part, p. 8086 - 8092 (2010/03/30)
A series of 4-(3-aryloxyaryl)quinolines with alcohol substituents on the terminal aryl ring was prepared as potential LXR agonists, in which an alcohol group replaced an amide in previously reported amide analogs. High affinity LXR ligands with excellent
