854885-59-9

Upstream product

• 501-53-1 benzyl chloroformate 
• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 140-10-3 (E)-3-phenylacrylic acid 
• 14440-98-3 N-(benzyloxycarbonyl)-DL-3-amino-3-phenylpropionic acid 

Downstream Products

• 138261-26-4 (1'S,6S)-1-(benzyloxycarbonyl)-3-(1'-phenyleth-1'-yl)-6-phenylperihydropyrimidin-4-one 
• 138261-27-5 (1'S,6R)-1-(benzyloxycarbonyl)-3-(1'-phenyleth-1'-yl)-6-phenylperihydropyrimidin-4-one 

Relevant academic research and scientific papers

Highly diastereoselective alkylation of perhydropyrimidin-4-ones directed toward the synthesis of α-substituted β-amino acids. 2

The alkylation of several enantiomerically pure perhydropyrimidin-4-ones at C5 is described. For the methylation reaction, mixtures of 5,6-trans -and cis-disubstituted adducts were obtained with high diastereomeric ratios, whereas only the 5,6-