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85504-88-7

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85504-88-7 Usage

General Description

(1S)-1-C-(4-carboxythiazolidin-2-yl)-L-arabinitol, also known as C4-thiazolidine-L-arabitol, is a compound that has potential therapeutic applications in treating diabetes and obesity. It is a synthetic compound that acts as an inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a role in the regulation of blood sugar levels. By inhibiting DPP-4, C4-thiazolidine-L-arabitol can help increase the levels of incretin hormones, which in turn can stimulate the release of insulin and reduce blood glucose levels. (1S)-1-C-(4-carboxythiazolidin-2-yl)-L-arabinitol has shown promising results in preclinical studies and may be a potential candidate for the development of new diabetes medications.

Check Digit Verification of cas no

The CAS Registry Mumber 85504-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,0 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85504-88:
(7*8)+(6*5)+(5*5)+(4*0)+(3*4)+(2*8)+(1*8)=147
147 % 10 = 7
So 85504-88-7 is a valid CAS Registry Number.

85504-88-7Relevant articles and documents

Proton and Zinc(II) Complexes of 2-(Polyhydroxyalkyl)thiazolidine-4-carboxylic acid Derivatives

Gajda, Tamas,Nagy, Laszlo,Burger, Kalman

, p. 3155 - 3160 (2007/10/02)

The protonation and zinc-ion co-ordination equilibria of 2-(polyhydroxyalkyl)thiazolidine-4-carboxylic acid derivatives have been studied by potentiometric titration in the range pH 1.5-8.In most cases the formation of complexes with a metal-to-ligand ratio of 1:2 was demonstrated, but at above pH 6 mixed-ligand complexes involving hydroxide-ion co-ordination were also observed.The protonation and complex-formation constants were shown to depend on the structure of the polyhydroxy chains.In the case of the protonation constants this is due to the rearrangement of the intramolecular hydrogen-bonding network, while the complex-formation constants depend on the conformation of the OH groups on the first carbon atoms of the polyol chains.

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