855218-49-4Relevant academic research and scientific papers
Regioselective two step synthesis of 3-substituted 2-aminoimidazo[1,2-a]pyrimidines
Carballares, Santiago,Cifuentes, Marta M.,Stephenson, Gregory A.
, p. 2041 - 2045 (2007)
A two step procedure for the regioselective synthesis of 3-substituted-2-aminoimidazo[1,2-a]pyrimidines is described. The key step is a Dimroth rearrangement of a mixture of 2 and 3-substituted aminoimidazo[1,2-a]pyrimidines that yields quantitatively one
Regioselective synthesis of 3-aminoimidazo[1,2- a ]-pyrimidines under continuous flow conditions
Butler, Ashlie J. E.,Thompson, Mark J.,Maydom, Patrick J.,Newby, James A.,Guo, Kai,Adams, Harry,Chen, Beining
, p. 10196 - 10202 (2015/02/19)
Multicomponent synthesis of 3-aminoimidazo[1,2-a]pyrimidines usually affords a product mixture containing varying amounts of the corresponding 2-amino regioisomer. Modified methods, particularly microwave heating, have been employed to suppress formation
