85523-00-8

Basic information

• Product Name: N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE
• Synonyms: N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE;N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE, 98;N-isopropyl-N,2-diMethylpropan-2-aMine;N-Isopropyl-N-methyl-tert-butylamine 98%
• CAS NO: 85523-00-8
• Molecular Formula: C₈H₁₉N
• Molecular Weight: 129.24
• Product Categories: Amines;C8;Nitrogen Compounds
• Mol File: 85523-00-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: -76.53°C (estimate)
• Boiling Point: 127 °C(lit.)
• Flash Point: 49 °F
• Appearance: /
• Density: 0.767 g/mL at 25 °C(lit.)
• Vapor Pressure: 18.7mmHg at 25°C
• Refractive Index: n20/D 1.419(lit.)
• CAS DataBase Reference: N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE(85523-00-8)
• EPA Substance Registry System: N-ISOPROPYL-N-METHYL-TERT-BUTYLAMINE(85523-00-8)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 85523-00-8(Hazardous Substances Data)

Usage

Uses

N-Isopropyl-N-methyl-tert-butylamine may be used to stabilize the borane-THF solutions. It may also be used for the synthesis of rotaxane, via Sonogashira coupling.

General Description

N-Isopropyl-N-methyl-tert-butylamine is a tertiary amine. BH3.THF stabilized by N-isopropyl N-methyl tert-butylamine is useful for the carbonyl reductions.

InChI:InChI=1/C8H19N/c1-7(2)9(6)8(3,4)5/h7H,1-6H3

Upstream product

• 7515-80-2 N-isopropyl-N-tert-butylamine 
• 50-00-0 formaldehyd 

Downstream Products

• 1118639-27-2 C₁₆H₂₃N 

Relevant articles and documents

Practical and Highly Enantioselective Ring Opening of Cyclic Meso-Anhydrides Mediated by Cinchona Alkaloids

The cinchona alkaloid-mediated opening of prochiral cyclic anhydrides in the presence of methanol leading to optically active hemiesters is described. Very structurally diverse anhydrides are converted into their corresponding methyl monoesters, and either enantiomer can be obtained with up to 99% ee by using quinine or quinidine as directing additive. After the reaction, the alkaloids can be recovered almost quantitatively and reused without loss of enantioselectivity. Additionally, a catalytic protocol which permits the substoichiometric use of quinidine in the presence of easily accessible pentamethylpiperidine (pempidine) is presented.