85554-26-3Relevant academic research and scientific papers
Synthesis of Di- and Triarylmethanes through Palladium-Catalyzed Reductive Coupling of N -Tosylhydrazones and Aryl Bromides
Xia, Yamu,Hu, Fangdong,Xia, Ying,Liu, Zhenxing,Ye, Fei,Zhang, Yan,Wang, Jianbo
, p. 1073 - 1086 (2017/02/24)
A palladium-catalyzed reductive coupling between N-tosylhydrazones and aryl bromides has been developed. The reaction provides an efficient method for the synthesis of diarylmethanes and triarylmethanes via the formation of C(sp2)-C(sp3) single bonds. This new methodology for the synthesis of diarylmethanes and triarylmethanes is featured by the ready availability of the starting materials, mild reaction conditions, and the tolerance of wide range of functional groups. The reaction follows a pathway including palladium carbene formation, migratory insertion, and reduction of the alkylpalladium(II) intermediate.
Palladium-catalyzed diarylmethyl C(sp3)-C(sp2) bond formation: A new coupling approach toward triarylmethanes
Xia, Ying,Hu, Fangdong,Liu, Zhenxing,Qu, Peiyuan,Ge, Rui,Ma, Chen,Zhang, Yan,Wang, Jianbo
, p. 1784 - 1787 (2013/06/26)
Palladium-catalyzed reductive coupling reactions between N-tosylhydrazones and aryl halides lead to the formation of C(sp3)-C(sp2) bonds. This approach provides a general route for the synthesis of triarylmethanes.
Towards a comprehensive hydride donor ability scale
Horn, Markus,Schappele, Ludwig H.,Lang-Wittkowski, Gabriele,Mayr, Herbert,Ofial, Armin R.
supporting information, p. 249 - 263 (2013/02/25)
Rates of hydride transfer from several hydride donors to benzhydrylium ions have been measured at 20 °C and used for the determination of empirical nucleophilicity parameters N and sN according to the linear free energy relationship log k20 °C=sN(N+E). Comparison of the rate constants of hydride abstraction by tritylium ions with those calculated from the reactivity parameters sN, N, and E showed fair agreement. Therefore, it was possible to convert the large number of literature data on hydride abstraction by tritylium ions into N and sN parameters for the corresponding hydride donors, and construct a reactivity scale for hydride donors covering more than 20 orders of magnitude.
