855630-49-8Relevant academic research and scientific papers
Synthetic and Organocatalytic Studies of Quinidine Analogues with Ring-Size Modifications in the Quinuclidine Moiety
Breman, Arjen C.,van der Heijden, Gydo,van Maarseveen, Jan H.,Ingemann, Steen,Hiemstra, Henk
, p. 14247 - 14256 (2016)
Six highly enantiopure analogues of [2.2.2] were synthesized with five- or seven-membered rings in the (original) quinuclidine skeleton. Five of these compounds were prepared through epoxide opening by a secondary cyclic amine, providing the nor- and homo
