855640-94-7

Upstream product

• 591-50-4 iodobenzene 
• 1527-89-5 3-methoxybenzonitrile 
• 318-13-8 [1,1'-biphenyl]-2-diazonium tetrafluoroborate 
• 90-41-5 2-phenylaniline 
• 99673-16-2 3-methoxy-benzoic acid biphenyl-2-ylamide 

Downstream Products

• 114721-72-1 5-acetonyl-6-(3-methoxy-phenyl)-phenanthridinium; bromide 

Relevant academic research and scientific papers

Rapid synthesis of polysubstituted phenanthridines from simple aliphatic/aromatic nitriles and iodo arenes: Via Pd(ii) catalyzed domino C-C/C-C/C-N bond formation

An efficient and straightforward method has been developed for the synthesis of polysubstituted phenanthridines from simple aryl iodides and alkyl/aryl nitriles via the palladium-catalyzed nucleophilic addition of aryl iodides to nitriles followed by casc

Preparation of Substituted Phenanthridines from the Coupling of Aryldiazonium Salts with Nitriles: A Metal Free Approach

A transition metal free approach for the synthesis of substituted phenanthridines from the coupling reaction of aryldiazonium tetrafluoroborates with nitriles has been developed. This operationally simple protocol proceeds through a substitution of aryldiazonium with nitriles followed by an intramolecular arylation to provide the corresponding phenanthridines in moderate to excellent yields. (Chemical Equation Presented).