855784-93-9Relevant academic research and scientific papers
Design, Synthesis, and Pharmacological Assay of Novel Compounds Based on Pyridazine Moiety as Potential Antitumor Agents
Ali, Yasmeen M.,Ismail, Mahmoud F.,Abu El-Azm, Fatma S. M.,Marzouk, Magda I.
, p. 2580 - 2591 (2019/08/20)
In an endeavor to develop antitumor agents, we made a credible survey regarding synthesis, structure, and pharmacological assay of novel pyridazine derivatives, so that 2-((6-(4-chloro-3-methylphenyl)pyridazin-3-yl)oxy)acetohydrazide 3 was utilized as sca
Synthesis of some heterocyclic systems of anticipated biological activities via 6-aryl-4-pyrazol-1-yl-pyridazin-3-one
Youssef,Marzouk,Madkour,El-Soll,El-Hashash
, p. 251 - 259 (2007/10/03)
6-Aryl-4-pyrazol-1-yl-pyridazin-3-one (1) reacted with a PCl 5-POCl3 mixture to give the 3-chloropyridazine derivative 3. Reaction of 3 with 2-hydroxybenzoylhydrazide and semicarbazide hydrochloride afforded 4 and 5. Reaction of 1 wi
