855871-94-2Relevant academic research and scientific papers
Enantioselective synthesis of cyclic α-aminoboronates via copper-catalyzed dearomative borylation of 4-quinolinols
Xu, Ming,Ouyang, Yizhao,Wang, Linghua,Zhang, Shuai,Li, Pengfei
supporting information, p. 3677 - 3680 (2022/04/07)
A highly enantioselective and regioselective dearomative borylation of 4-quinolinols was developed using a Cu(i)/(R,R)-Ph-BPE catalyst for efficient synthesis of unprecedented heterocyclic α-amino boronates, a new class of compounds potentially relevant to drug discovery, in generally excellent yields and enantioselectivities. The products were also useful intermediates for highly functionalized tetrahydroquinolines and cyclic α-aminoboronate derivatives.
ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE
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Page/Page column 65, (2008/12/04)
There is provided compounds of formula I wherein R1, R2, R3, R4, X1, X2 and A have meanings given in the description. Also provided are medical uses of such compounds, such as the killing c
Preparation of quinoline hexose analogs as novel chloroquine-resistant malaria treatments (1). Synthesis of 4-hydroxyquinoline-β-glucosides
Suzuki, Hiroshi,Aly, Nagwa S. M.,Wataya, Yusuke,Kim, Hye-Sook,Tamai, Ikumi,Kita, Masaki,Uemura, Daisuke
, p. 821 - 824 (2008/02/13)
Quinoline hexose analogs are expected to be useful as novel agents for treatment of chloroquine-resistant malaria. Here, we report preparation of 4-hydroxy quinoline-β-glucosides from anilines in 4 steps.
