85588-56-3Relevant academic research and scientific papers
(13)C NMR SPECTROSCOPY OF SOME HETISINE SUBTYPE C20-DITERPENOID ALKALOIDS AND THEIR DERIVATIVES
Gonzalez, A. G.,Fuente De La, G.,Reina, M.,Diaz, R.,Timon, I.
, p. 1971 - 1974 (1986)
The 13C NMR spectra of the diterpenoid alkaloids hetisine; hetisinone; 13-acetylhetisinone; cardiopetamine, and 15-acetylcardiopetamine, as well as certain of their derivatives, were obtained in the Fourier mode at 50.32 MHz.With the aid of proton decoupling techniques, SFORD and SFDS, and chemical shift comparisons, selfconsistent assignments of nearly all the resonance have been made.
Diterpenoid alkaloids and flavonoids from Delphinium trichophorum
Lin, Chao-Zhan,Zhao, Zhong-Xiang,Xie, Si-Min,Mao, Ju-Hua,Zhu, Chen-Chen,Li, Xiao-Hui,Bairi, Zeren-Dawa,Kangsa, Suolang-Qimei,Dun, Zhu,Xiong, Tian-Qin,Wu, Ai-Zhi
, p. 88 - 95 (2014/01/06)
Five hetisane-type C20-diterpenoid alkaloids, trichodelphinines A-E, one delnudine-type C20-diterpenoid alkaloid, trichodelphinine F and three known flavonoids, quercetin, quercetin 3-O-β-d-glucopyranoside, and quercetin 3-O-β-d-glucopyranoside-7-O-α-l-arabinopyranoside, were isolated from whole plants of Delphinium trichophorum Franch. Their structures were elucidated on the basis of extensive spectroscopic analysis, including HSQC, HMBC, 1H-1H COSY, NOESY and X-ray crystallographic analysis, and from chemical evidence. The cytotoxic activities of the diterpenoid alkaloids were evaluated using the MTT method, and the IC 50 values of their cytotoxicity against A549 cancer cells ranged from 12.03 to 52.79 μM.2013 Elsevier Ltd. All rights reserved.
