85590-86-9

Upstream product

• 85590-85-8 1-(benzo[d][1,3]dioxol-5-yl)-2-(4-nitrophenyl)ethanone 
• 274-09-9 Methylenedioxybenzene 
• 50434-36-1 4-nitrophenylacetyl chloride 

Downstream Products

• 85590-88-1 1-(6-Amino-benzo[1,3]dioxol-5-yl)-2-(4-amino-phenyl)-ethanone 
• 69828-29-1 4-(2-methyl-6,7-methylenedioxy-4-quinazolinylmethyl)aniline 
• 69813-73-6 N-<4-ethyl-(2-methyl-6,7-methylenedioxy-4-quinazolinylmethyl)-phenyl>carbamate 
• 85591-04-4 N-[4-(6-Methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-phenyl]-acetamide 
• 85590-87-0 2'-(acetylamino)-2-(4-acetylaminophenyl)-4',5'-methylenedioxyacetophenone 

Relevant academic research and scientific papers

THE SYNTHESIS OF SOME COMPLEX QUINAZOLINE DERIVATIVES CONTAINING ONE OR TWO QUINAZOLINE RINGS AND CARRYING AMINO, ACYLAMINO, ESTER AND/OR CARBAMATE FUNCTIONAL GROUPS IN THEIR SIDE CHAINS

The scope of the Bischler synthesis has been extented to the synthesis of complex quinazoline derivatives 3b-3d, 5a-5f, 6a, 6b, 7 and 8.Reductive cleavage of the C-N bond of all 4-(N-monosubstituted aminomethyl)quinazolines tested took place on treatment with ethanol in the presence of acids or bases.