85599-06-0Relevant academic research and scientific papers
Synthesis of P-stereogenic secondary phosphine oxides using α-d-glucosamine as a chiral precursor
Copey, Laurent,Jean-Gérard, Ludivine,Andrioletti, Bruno,Framery, Eric
, p. 543 - 545 (2016/01/20)
Secondary phosphine oxides were synthesized using a two-step procedure: a basic hydrolysis of oxazaphospholidine SP-2 to form the secondary phosphinate RP-4, followed by the stereoselective nucleophilic attack of organometallic reagents to obtain the expected enantioenriched secondary phosphine oxides.
Stereospecific nucleophilic substitution of optically pure H-phosphinates: A general way for the preparation of chiral P-stereogenic phosphine oxides
Xu, Qing,Zhao, Chang-Qiu,Han, Li-Biao
supporting information; experimental part, p. 12648 - 12655 (2009/05/09)
Contrary to the generally held view, it is found that the rapid epimerization of (-)-menthyl (RP)-phenylphosphinate under basic conditions is not due to the so far believed inherent stereolability of its corresponding anion but due to a reactio
