856003-84-4Relevant academic research and scientific papers
Concise syntheses of selective inhibitors against α-1,3- galactosyltransferase
Zhang, Guo-Liang,Zhang, Li-He,Ye, Xin-Shan
, p. 5062 - 5068 (2010)
Several iminosugar-based uridine diphosphate galactose (UDP-Gal) mimetics 1-4 including d- and l-epimers were designed and synthesized by concise routes, and these synthetic compounds were evaluated for the inhibition of α-1,3- and β-1,4-galactosyltransfe
Synthesis of Iminosugar-Containing KRN7000 Analogues
Zhang, Lei,Ye, Xin-Shan
, p. 1001 - 1008 (2017/06/27)
Three new iminosugar-containing KRN7000 (also referred to as α-GalCer) analogues were designed and synthesized. In the design, the galactose moiety of KRN7000 was replaced by iminosugars and the iminosugar structures were connected with ceramide in differ
Synthetic iminosugar derivatives as new potential immunosuppressive agents
Ye, Xin-Shan,Sun, Fang,Liu, Min,Li, Qin,Wang, Yuhang,Zhang, Guisheng,Zhang, Li-He,Zhang, Xiao-Lian
, p. 3688 - 3691 (2007/10/03)
Several iminosugar derivatives were synthesized, and their effects on the secretion of IL-4 and IFN-γ from the mouse splenocytes were examined. The effects on membrane expression of other T cell-associated molecules (CD3, CD4, CD8) and B cell-associated m
