856016-96-1Relevant academic research and scientific papers
The development and scope of a versatile tandem Stille-oxa-electrocyclization reaction
Tambar, Uttam K.,Kano, Taichi,Zepernick, John F.,Stoltz, Brian M.
, p. 345 - 350 (2008/02/04)
A palladium-catalyzed tandem Stille-oxa-electrocyclization reaction has been developed for the convergent preparation of highly substituted polycyclic pyran systems. The strategy presented in this letter is an alternative to the known methods for construc
Convergent and diastereoselective synthesis of the polycyclic pyran core of saudin
Tambar, Uttam K.,Kano, Taichi,Zepernick, John F.,Stoltz, Brian M.
, p. 8357 - 8364 (2007/10/03)
The natural product saudin was found to induce hypoglycemia in mice and, therefore, could be an appealing lead structure for the development of new agents to treat diabetes. A diastereoselective tandem Stilleoxa- electrocyclization reaction has been devel
Progress toward the total synthesis of saudin: Development of a tandem Stille-oxa-electrocyclization reaction
Tambar, Uttam K.,Kano, Taichi,Stoltz, Brian M.
, p. 2413 - 2416 (2007/10/03)
(Chemical Equation Presented) A diastereoselective tandem Stille-oxa-electrocyclization reaction provides access to the core of the diterpenoid natural product saudin. Additionally, this new reaction sequence was extended to the convergent preparation of
