85612-96-0Relevant articles and documents
Synthesis and biological evaluation of 14,15-dehydro-LTA4 analog
Garcia, Mylene,Durand, Thierry,Rossi, Jean Claude,Zarini, Simona,Bolla, Manlio,Folco, Giancarlo,Wheelan, Pat,Sala, Angelo
, p. 105 - 108 (1997)
New stable leukotriene A4 analog with acetylenic function in positions 14,15 has been synthesized. Conversion of this analog to the corresponding LTC4 derivative and the structural and biological characterization are presented.
Smooth muscle contractile activities of leukotriene analogues
Cho,Ueda,Funahashi,Koda
, p. 3326 - 3329 (2007/10/02)
Chemical modification in the hydrophilic and hydrophobic regions of leukotrienes was investigated in relation to their smooth muscle contractile activities. The conjugated diene or triene moeity in the hydrophobic region is crucial for potent contractile