85616-28-0Relevant academic research and scientific papers
SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES
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Page/Page column 14-15; 40; 68, (2019/11/12)
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Substituted heteroaryl amide modulators of glucocorticoid receptor, AP-1, and/or NF-kB activity and use thereof
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Page/Page column 35, (2008/06/13)
The present invention relates to new class of non-steroidal compounds which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including obesity, diabetes, inflammatory- and immune-associ
Preparation and Photocyclisation of Bromomethyl 1,2-Diketones
Hamer, Neil K.
, p. 61 - 64 (2007/10/02)
A simple preparative route to the title compounds is given involving bromine addition to α-ethoxyvinyl ketones and subsequent hydrolysis.These compounds undergo efficient photocyclisation with retention of the halogen to hydroxycyclobutanone and hydroxycy
